UW Med: simultaneous publication of 10 research papers exploring relationship between chronic pain and traumatic brain injury

Dr. Jeanne Hoffman

UW Medicine’s Dr. Jeanne Hoffman and colleagues from across the nation were poised to celebrate their exceptional achievement: the simultaneous publication of 10 research papers that explore the relationship between chronic pain and traumatic brain injury.

Then came another, even rarer, reason for jubilation: They learned that their papers would fill the current issue of The Journal of Head Trauma Rehabilitation, cover to cover. 

It was the scientific equivalent of a baseball triple play, a rare and noteworthy achievement.

“We've all been a little bit bowled over,” said Hoffman, a professor of rehabilitation medicine at the University of Washington School of Medicine. 

“Typically, topical issues are only part of a larger journal. We definitely managed to fill the whole thing.”

Hoffman co-authored the preface and nine of 10 articles in the series. The 10th, on the use of cannabis and opiates in association with TBI, was co-authored by Amy Starosta, assistant professor of rehabilitation medicine at the UW School of Medicine. 

Research has shown a high prevalence of long-term chronic pain among people who had experienced traumatic brain injury. In surveying more than 3,800 people from that population, Hoffman and her colleagues found that about 60% reported current or previous chronic pain. 

“What we saw is really high rates of chronic pain across many years post-injury,” Hoffman said. “These are  people who even 25 or 30 years out have about the same rates of chronic pain. Around 46% of our group are reporting experiencing current chronic pain, which tells us that they're probably not getting the right kind of treatment.”

Another complication for doctors: The sources of pain associated with TBI vary. Pain can stem from the brain injury itself, or from soft tissue or muscles and bones.. Neuropathic pain and cognitive difficulties are seen as significant barriers to the effective treatment of chronic pain. 

Addressing chronic pain more effectively in individuals with TBI has the potential to improve their health and quality of life. People with traumatic brain injuries who also have chronic pain tend to report more disability, worse psychological health and greater difficulty reintegrating into their communities. 

Addressing chronic pain in this patient population is especially important, given the heightened focus on opioid addiction globally. 

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